Our research program is centered around compartmentalized G protein signaling by internalized G protein-coupled receptors (GPCRs). Our main objective is to understand the mechanistic basis behind compartmentalized GPCR signaling at a near-atomic level, and to study its direct implications on a variety of physiological and pathophysiological conditions including cancer metastasis, nociception, and salt/water homeostasis.
The Thomsen Lab is led by Alex Thomsen, an assistant professor in the Department of Molecular Pathobiology at NYU.
Research Interests
We are investigating GPCR signaling at a near-atomic resolution and the physiological functions of endosomal GPCR signaling
Recent Publication
“Structure of an Endosomal Signaling GPCR–G Protein–β-Arrestin Mega-Complex” has been published in Nature Structural & Molecular Biology
Who We Are
We are looking for motivated and creative students and postdocs to join our lab at New York University
